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Flow cytometry laboratory purification and decoration standards and equipment configuration CEIDI

文章出处:Technology|阅读量:349|发表时间:2021-03-22

After entering the 21st century, flow cytometry (FCM) has become more and more perfect. Based on its unique cell sorting principle and powerful fluorescent labeling technology, its application in clinical laboratories has comprehensively covered blood tumors. It is believed that the technical principles involved in the diagnosis and prognostic monitoring of minimal residual disease and various solid tumors have also been well-known and recognized by the public, and have become an irreplaceable important tool in the field of cytology and medical testing. It provides a strong data basis for clinical medical diagnosis. The flow cytometry laboratory, as a laboratory with top technologies in the medical field, provides a strong data basis for clinical medical diagnosis. Such laboratories can carry out items such as immune typing and residual disease monitoring of lymphohematopoietic system tumors, cellular immunity, platelet function testing, HLA-b27 testing, PNH testing, and intracellular cytokine testing. The construction of the laboratory also has a certain degree of professionalism due to the combination of experimental functions and the professional content of many high-precision subjects.

In the international standard classification, flow cytometry laboratory involves laboratory medicine, analytical chemistry, radiation protection, radiation measurement, nuclear energy engineering, medical equipment, biology, botany, and zoology. In the Chinese standard classification, flow cytometry laboratory involves basic standards and general methods, integration of radiation protection and monitoring, radiation protection monitoring and evaluation, emergency response and treatment of nuclear radiation accidents, radiation health protection, laboratory basic equipment, basic disciplines Comprehensive.

The cell laboratory needs to meet the overall 10,000-level and local-level 100-level purification standards, and it needs to be equipped with biological safety cabinets, ultra-clean workbenches, high-performance desktop low-temperature centrifuges, flow cytometers, PCR machines, CO2 incubators, blood cell analyzers, Flow cytometers, cell function analyzers, liquid nitrogen devices and other equipment are suitable for the separation, preparation, expansion, and cultivation of a variety of cells, as well as for the application of quality control systems and quantitative standards.

For engineering constructions that require cleanliness, organizations/enterprises will routinely seek help from EPC (Engineering General Contracting) companies that are professionally active in the field of clean engineering. Research in laboratories such as biomolecules and cell analysis must be conducted at a certain temperature, humidity, and temperature. The research is carried out under the environment of illuminance, PH value and cleanliness, so the selection of decoration materials and the requirements of clean room air purification are extremely high. In particular, the instruments and equipment in this type of laboratory are very expensive, with a single piece costing hundreds of thousands. In this case, a reasonable functional layout design is a major way for laboratories to save money.

For example, cell research laboratories must meet the design layout of GMP laboratories, and the functional rooms can be divided into cell operation rooms, culture rooms, cell preservation rooms, consumables storage rooms, cleaning and disinfection rooms, and sanitary ware rooms. Each independent room here has strict regulations on the temperature and humidity, fresh air volume, state, and illuminance of the laboratory environment. Where is the transfer window set? How to set up a clean corridor? It's all a science. CEIDI Xidi has accumulated rich experience in the construction of such laboratories. How to build a laboratory that meets various standards and can create practical benefits for enterprises under limited budget conditions is CEIDI Xidi's long-standing pursuit.

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