The so-called cell laboratory is a laboratory that uses biological units with complete vitality as the research objects of basic research and clinical application. Different from general laboratories, tissue cell culture technology research must maintain aseptic operation due to the particularity of the research object. Therefore, when constructing its research laboratory, functional partitions and equipment configuration must avoid the influence of microorganisms and other harmful factors. . In this article, CEIDI takes the cell laboratory project of a large medical institution as an example, and lectures on the design content of the cell culture laboratory. It should be noted that the scale of this project is relatively large compared to the general thematic research cell culture laboratory.

Project overview and design parameters of cell laboratory decoration

A complete cell laboratory is usually divided into 4 floors, of which the first floor is the logistics support facility room, the second floor is the experimental stem cell production workshop, the third floor is the biopharmaceutical pilot production workshop, and the fourth floor is the office and public laboratory functional rooms. . Of course, you don’t have to follow this floor order, you can plan specifically according to your own needs. The detailed layout is as follows:

Logistic support facilities rooms: mainly include 5 rooms: stem cell bank, spare parts bank, dressing room, water making room, and power distribution room. Among them, the stem cell bank has a clean demand.

Experimental stem cell production workshop: mainly includes cell culture room, suite culture room, quality control room, and sterilization room, washing room, liquid nitrogen storage room, dressing room, clean room, laundry room, liquid distribution room, consumables library, internal The 12 rooms in the corridor.

Biopharmaceutical pilot production workshop: mainly including experimental area, experimental area corridor, reserved area corridor, first shift room, second shift room, cell culture room, purification room, fermentation room, filling room, sterile equipment room, These 11 rooms in the spare laboratory.

Functional rooms such as offices and public laboratories: mainly include two rooms: staff office and public laboratory.

Design parameters of cell laboratory decoration

The design parameters of cell laboratory decoration are divided into two parts, namely: outdoor design parameters and indoor design parameters. The detailed parameters are as follows:

Outdoor design parameters: summer outdoor air conditioner calculated dry bulb temperature 30.6℃, wet bulb temperature 24.5℃; winter outdoor air conditioner calculated dry bulb temperature -25℃, relative humidity 68%.

Indoor design parameters: The indoor design temperature of the 10,000-class clean area is 20~24℃, and the relative humidity is 45%~60%; the indoor design temperature of the 100,000-class clean area is 18~26℃, and the relative humidity is 45%~65%.

Research on adaptability of cell laboratory decoration

In fact, whether it is cell laboratory decoration or other types of laboratory decoration, only 32% of the laboratories remain intact after decoration, and the rest will have subsequent reconstruction needs. Therefore, CEIDI reminds us that it is very important to study the adaptability before decoration. It is necessary to improve the quality of decoration, adopt advanced technology and equipment, and achieve specialization, commercialization and serialization. At the same time, we must pay attention to the design of safety, energy saving, environmental protection, etc., and also consider the realization of sustainable development at the technical level to meet the requirements of future upgrades.